There have been reports that a couple of Microsoft security updates for the month of June are causing some issues with VMware vCenter, the main one is KB 980773 – this is an update to DotNet. While I am in the process of rebuilding my test lab this will be something I will defiantly test out prior to updating our production vCenter server this month. For a little more information of the subject, there is a small discussion going on the VMware forums regarding this issue, this should be a decent source of information until more is discovered later on. http://communities.vmware.com/message/1549225
http://communities.vmware.com/message/1549225
I just installed the latest Windows Updates on my lab vCenter server (4.0 U1 build 208111). I am still able to access vCenter and do not get the error mentioned in the forums article.
VMware released a KB article regarding this issue – http://kb.vmware.com/kb/1022611